This alignment (RN, 7/15/03) is based on most available Mouse and Drosophila Wnt proteins.

MOUSEWNT1 ------------------MGLWALLPSWVSTTLLLALTALPAALAANSSG
MOUSEWNT2 --------------------------------MNVPLGGIWLWLPLLLTW
MOUSEWNT2B MLKLQGEDEAAQLAPRRARVPVPRPTAPDVSPSSARLGLACLLLLLLLT-
MOUSEWNT3 ------------------------MEPHLLGLLLGLLLSGTRVLAGYPIW
MOUSEWNT3A ------------------------MAP--LGYLL-VLCSLKQALGSYPIW
MOUSEWNT4 ------------------------------MSPRSCLRSLRLLVFAVFSA
MOUSEWNT5A ----MKKPIGILSPGVALGTAGGAMSSKFFLMALATFFSFAQVVIEANSW
MOUSEWNT5B ----------MLVPG-HWDGLRPAMPSLLLVVVAALLSSWAQLLTDANSW
MOUSEWNT6 --------------------MLPPVPSRL-------GLLLLLLCPAHVDG
MOUSEWNT7A ------------------------------MTRKARRCLGHLFLSLGIVY
MOUSEWNT7B ------------------------------MHRNFRKWIFYVFLCFGVLY
MOUSEWNT8A -----------------------------------MGHLLMLWVAAGMCY
MOUSEWNT8B -------------------------------------MFLMKPVCVLLVT
MOUSEWNT9A ----------------------MLDGSLLARWLAAAFGLTLLLAALRPSA
MOUSEWNT9B --------------------------MRPAPALALAALCLLVLPAAAAAA
MOUSEWNT10A -----------MGSAHPRPWLRLPQGPQPRPEFWALLFFLLLLAAAVPRS
MOUSEWNT10B ----------------------MLEEPRSRPPPLGLAGLLFL--ALFSRA
MOUSEWNT11 --------------------------MRARPQVCEALLFALALHTGVCYG
MOUSEWNT16 ------------------------MDRAALLALPSLCALWAAVLSLLPCG
DrosophilaWg ------------------MDISYIFVICL-MALCSGGSSLSQVEGKQKSG
DrosophilaWnt2 --------------------------------------MWKIHNKLLIYI
DrosophilaWnt3/5_short_ --------------------------------------------------
hydraWnt ------------------------MGT--TRYKETLLCFLLIFMETQAQL
C_elegans_egl20 ----------------------MQFFICLIFLFVLLVYGQYSPPSATYST

MOUSEWNT1 RWWGIVNIASST——-NLLTDSKSL—-QLVLEPSLQ-LLSRKQRR
MOUSEWNT2 LTPEVSSSWWYM——-RATGGS–S—-RVMCDNVPG–LVSRQRQ
MOUSEWNT2B LPARVDTSWWYI——-GALG—-A—-RVICDNIPG–LVSRQRQ
MOUSEWNT3 WSLALGQQYTSL——-ASQPL———-LCGSIPG–LVPKQLR
MOUSEWNT3A WSLAVGPQYSSL——-STQPI———-LCASIPG–LVPKQLR
MOUSEWNT4 AASNWLYLAKLS——-SVGSIS–E—-EETCEKLKG–LIQRQVQ
MOUSEWNT5A WSLGMNNPVQMS——-EVYIIG–A—-QPLCSQLAG–LSQGQKK
MOUSEWNT5B WSLALN-PVQRP——-EMFIIG–A—-QPVCSQLPG–LSPGQRK
MOUSEWNT6 LWWA—————VGSPLVMDP—-TSICRKARR–LAGRQAE
MOUSEWNT7A LRIGGFSSVVAL——-GASII———–CNKIPG–LAPRQRA
MOUSEWNT7B VKLGALSSVVAL——-GANII———–CNKIPG–LAPRQRA
MOUSEWNT8A PALGAS———————————-AWSVNNFLIT
MOUSEWNT8B CVLHRSH———————————AWSVNNFLMT
MOUSEWNT9A AYFGLTGSEPLTILPL–TLETEAAAQA—-HYKACDRLK–LERKQRR
MOUSEWNT9B AYFGLTGREVLTPFPGLGTAAAPAQAGA—-HLKQCDLLK–LSRRQKQ
MOUSEWNT10A APNDILGLRLP———PEPVLNAN—-TVCL-TLPG–LSRRQME
MOUSEWNT10B LSNEILGLKLP———GEPPLTAN—-TVCL-TLSG–LSKRQLG
MOUSEWNT11 IKWLALSKTPA——–ALALNQTQH—-CKQ—LEG–LVSAQVQ
MOUSEWNT16 TQGNWMWLGIASFGVPEKLGCADLP——————LNSRQKE
DrosophilaWg RGRGSMWWGIAK——-VGEPNNITP—-IMYMDPAIHSTLRRKQRR
DrosophilaWnt2 LWIMEIRLVSSF——-TSAML———–CGRIPG–LTPGQRN
DrosophilaWnt3/5_short_ ———————————-MCYSAIG–LSNSQKK
hydraWnt W-MALGTQTSAI——-ESRPRSSIN—-KNLCRALY—LHHYQRT
C_elegans_egl20 QQVPYNWLTLAFVGSNDYLPRPHYHSTDREHFKELCRRLDG–LNPNQQA

MOUSEWNT1 LIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPT———APGPH
MOUSEWNT2 LCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTL——DR–DHS
MOUSEWNT2B LCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTL——DR–DHT
MOUSEWNT3 FCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTI——DD–SLA
MOUSEWNT3A FCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTV——SN–SLA
MOUSEWNT4 MCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTL——D—SLP
MOUSEWNT5A LCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTV——D—NTS
MOUSEWNT5B LCQLYQEHMSYIGEGAKTGIRECQHQFRQRRWNCSTV——D—NTS
MOUSEWNT6 LCQAEPEVVAELARGARLGVRECQFQFRFRRWNCSS———–HSK
MOUSEWNT7A ICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSAL——GE–R-T
MOUSEWNT7B ICQSRPDAIIVIGEGAQMGIDECQHQFRFGRWNCSAL——GE–K-T
MOUSEWNT8A GPKAYLTYTASVALGAQIGIEECKFQFAWERWNCPEH———AFQF
MOUSEWNT8B GPKAYLVYSSSVAAGAQSGIEECKYQFAWDRWNCPER———ALQL
MOUSEWNT9A MCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLE——GR—–
MOUSEWNT9B LCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLE——G——
MOUSEWNT10A VCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSL——ETRNKVP
MOUSEWNT10B LCLRSPDVTASALQGLHIAVHECQHQLRDQRWNCSAL——EGGGRLP
MOUSEWNT11 LCRSNLELMRTIVHAARGAMKACRRAFADMRWNCSSI——ELA—P
MOUSEWNT16 LCKRKPYLLPSIREGARLGIQECRSQFRHERWNCMV–ATTTSTQLATAP
DrosophilaWg LVRDNPGVLGALVKGANLAISECQHQFRNRRWNCSTR——NFSRGKN
DrosophilaWnt2 MCREMPDALIALGEGHQLGAQECQHQFRGHRWNCSEV——WQ–R-N
DrosophilaWnt3/5_short_ QCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTT——N—DET
hydraWnt VCLNYTDLMLSVAEGIRLGIDECQVQFKHRKWNCTIN——EH–GTS
C_elegans_egl20 LCAENPFSIPFVARGVREAIRECENKFKFERWNCSSRDEVTETRHGKFQD

MOUSEWNT1 LFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRG–
MOUSEWNT2 LFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKG–
MOUSEWNT2B VFGRAMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRG–
MOUSEWNT3 IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHK—
MOUSEWNT3A IFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQ—
MOUSEWNT4 VFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTV—-
MOUSEWNT5A VFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRA—–
MOUSEWNT5B VFGRVMQIGSRETAFTYAVSAAGVVNAISRACREGELSTCGCSRAA—-
MOUSEWNT6 AFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQAPRGRAP
MOUSEWNT7A VFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQ—
MOUSEWNT7B VFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQ—
MOUSEWNT8A STHNRLRAATRETSFIHAIRSAAIMYAVTKNCSMGDLENCGCDESQ—-
MOUSEWNT8B SSHGGLRSANRETAFVHAISSAGVMYTLTRNCSLGDFDNCGCDDSR—-
MOUSEWNT9A YRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCD——-
MOUSEWNT9B -RTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCD——-
MOUSEWNT10A YESPIFSRGFRESAFAYAIAAAGVVHAVSNACALGKLKACGCDASRRGDE
MOUSEWNT10B HHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQ
MOUSEWNT11 NYLLDLERGTRESAFVYALSAATISHTIARACTSGDLPGCSCG——-
MOUSEWNT16 LFGYELSSGTKETAFIYAIMAAGLVHSVTRSCSAGNMTECSCDTT—–
DrosophilaWg LFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRS
DrosophilaWnt2 VFAHVIPTASREAAYTYAIASAGAAYRVTAACARGNISTCGCDVRHKATP
DrosophilaWnt3/5_short_ VFGPMTSLAAPEMAFIHALAAATVTSFIARACRDGQLASCSCSRGS—-
hydraWnt VFGPIITTASRESAFISGIISAGVAFSVTESCAEGKSVHCRCDNSVR—
C_elegans_egl20 ILGKTLRSANKEAAFLNAIMAASIVHSITKGCNTGNLTECGCDSKPGMQR

MOUSEWNT1 ————————————PG–GPDWHWGGCS
MOUSEWNT2 ———————————SAKDS–KGTFDWGGCS
MOUSEWNT2B ———————————RHHDQ–RGDFDWGGCS
MOUSEWNT3 ———————————–GPP–GEGWKWGGCS
MOUSEWNT3A ———————————–GSP–GEGWKWGGCS
MOUSEWNT4 ———————————HGVS—PQGFQWSGCS
MOUSEWNT5A ———————————RPKDL–PRDWLWGGCG
MOUSEWNT5B ———————————RPKDL–PRDWLWGGCG
MOUSEWNT6 PRPSGLL—————–GTPGPPGPTGSPDA–SAAWEWGGCG
MOUSEWNT7A ———————————GQYHW–DEGWKWGGCS
MOUSEWNT7B ———————————GYYNQ–AEGWKWGGCS
MOUSEWNT8A ———————————–NGKTGGHGWIWGGCS
MOUSEWNT8B ———————————–NGQLGGQGWLWGGCS
MOUSEWNT9A ——————————-EAPDLEN–REAWQWGGCG
MOUSEWNT9B ——————————-DSPGLES–RQAWQWGVCG
MOUSEWNT10A EAFRRKLHRLQLDALQRGKGLSHGVPEHPAILPASPGL–QDSWEWGGCS
MOUSEWNT10B DRLRAKL–LQLQALSRGKTFPISQPSPVPGSVPSPGP–QDTWEWGGCN
MOUSEWNT11 ——————————-PVPGEPP–GPGNRWGGCA
MOUSEWNT16 ——————————LQNGGSPS—EGWHWGGCS
DrosophilaWg PQANH————————–QAGSVAG–VRDWEWGGCS
DrosophilaWnt2 ——————————–TGGGTP–DEPWKWGGCS
DrosophilaWnt3/5_short_ ———————————RPKQL–HDDWKWGGCG
hydraWnt ———————————–GQT–DEGWRWGGCN
C_elegans_egl20 ——————————YQAESDPSMSRDQFSWGGCS

MOUSEWNT1 DNIDFGRLFGREFVDSGEKGR——–DLRFLMNLHNNEAGRTTVFSE
MOUSEWNT2 DNIDYGIKFARAFVDAKERK——-GKDARALMNLHNNRAGRKAVKRF
MOUSEWNT2B DNIHYGVRFAKAFVDAKEKR——-LKDARALMNLHNNRCGRTAVRRF
MOUSEWNT3 EDADFGVLVSREFADAREN——–RPDARSAMNKHNNEAGRTTILDH
MOUSEWNT3A EDIEFGGMVSREFADAREN——–RPDARSAMNRHNNEAGRQAIASH
MOUSEWNT4 DNIAYGVAFSQSFVDVRERSK—–GASSSRALMNLHNNEAGRKAILTH
MOUSEWNT5A DNIDYGHPFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNL
MOUSEWNT5B DNVEYGYRFAKEFVDAREREKNFAKGSEEQGRALMNLQNNEAGRRAVYKM
MOUSEWNT6 DDVDFGDEKSRLFMDAQHKRGR—–G-DIRALVQLHNNEAGRLAVRSH
MOUSEWNT7A ADIRYGIGFAKVFVDAREI——–KQNARTLMNLHNNEAGRKILEEN
MOUSEWNT7B ADVRYGIDFSRRFVDAREI——–KKNARRLMNLHNNEAGRKVLEDR
MOUSEWNT8A DNVEFGEKISRLFVDSLEK——–GKDARALVNLHNNRAGRLAVRAS
MOUSEWNT8B DNVGFGEAISKQFVDALET——–GQDARAAMNLHNNEAGRKAVKGT
MOUSEWNT9A DNLKYSSKFVKEFLG———RRSSKDLRARVDFHNNLVGVKVIKAG
MOUSEWNT9B DNLKYSTKFLSNFLGP——–KRGSKDLRARADAHNTHVGIKAVKSG
MOUSEWNT10A PDVGFGERFSKDFLDS——–REPHRDIHARMRLHNNRVGRQAVMEN
MOUSEWNT10B HDMDFGEKFSRDFLDS——–REAPRDIQARMRIHNNRVGRQVVTEN
MOUSEWNT11 DNLSYGLLMGAKFSDAPMKV—-KKTGSQANKLMRLHNSEVGRQALRAS
MOUSEWNT16 DDVQYGMWFSRKFLDLPIRNT—TGKESRVLLAMNLHNNEAGRQAVAKL
DrosophilaWg DNIGFGFKFSREFVDTGERGR——–NLREKMNLHNNEAGRAHVQAE
DrosophilaWnt2 ADVDFGMRYARRFMDAREL——–ERDSRTLMNLHNNRAGRTLVKKM
DrosophilaWnt3/5_short_ DNLEFAYKFATDFIDSREKE——TNVKARSLMNLHNNEAGRRAVIKK
hydraWnt RPITYGIWFSQLFIDQVEKIVK—-KRKDPRKIMNLHNNKAGREVIKNL
C_elegans_egl20 DNVPHGIRYAKKFLDDWETAQ—FDKTKNVAHLVRRHNNFVGREAIAQN

MOUSEWNT1 MRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGS
MOUSEWNT2 LKQECKCHGVSGSCTLRTCWLAMADFRKTGEYLWRKYNGAIQVVMNQDGT
MOUSEWNT2B LKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVTATQDGA
MOUSEWNT3 MHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRE
MOUSEWNT3A MHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRE
MOUSEWNT4 MRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGS
MOUSEWNT5A ADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGK
MOUSEWNT5B ADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRITRQGK
MOUSEWNT6 TRTECKCHGLSGSCALSTCWQKLPPFREVGARLLERFHGASRV——-
MOUSEWNT7A MKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASR
MOUSEWNT7B MKLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASR
MOUSEWNT8A TKRTCKCHGISGSCSIQTCWLQLADFRQMGNYLKAKYDRALKIEMDKRQL
MOUSEWNT8B MKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDL–LQ-
MOUSEWNT9A VETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETSLKVGSTTNEA
MOUSEWNT9B LRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEA
MOUSEWNT10A MRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRNRFHRATLIRPHNRNG
MOUSEWNT10B LKRKCKCHGTSGSCQFKTCWRAAPEFRAIGAALRERLSRAIFIDTHNRNS
MOUSEWNT11 LETKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGT
MOUSEWNT16 MSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHFLKDKYEN-SIQISDKTKR
DrosophilaWg MRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRV—-QVT
DrosophilaWnt2 LRTDCKCHGVSGSCVMKTCWKSLPPFRLVGDRLMMKYQKAKTVQAVKGKR
DrosophilaWnt3/5_short_ ARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGR
hydraWnt LQTECKCHGTSGNCNLKTCWRSQPHFSEIGKILKEKYDSAHEMEFLYKVK
C_elegans_egl20 IRRQCRCHGVSGSCEFKTCWLQMQKFSQVSDLLKKRYDHFAVQVTRKATK

MOUSEWNT1 NRASRAELLRLEPEDPAHKP—–PSPHDLVYFEKSPNFCTYSGRLGTA
MOUSEWNT2 G———FTVANKRFKK—–PTKNDLVYFENSPDYCIRDREAGSL
MOUSEWNT2B N———FTAARQGYRH—–ATRTDLVYFDNSPDYCVLDKASGSL
MOUSEWNT3 S-RG–WVETLRAKYALFKP—–PTERDLVYYENSPNFCEPNPETGSF
MOUSEWNT3A S-RG–WVETLRPRYTYFKV—–PTERDLVYYEASPNFCEPNPETGSF
MOUSEWNT4 S-RA——LVPRNAQFKP—–HTDEDLVYLEPSPDFCEQDIRSGVL
MOUSEWNT5A ———-LVQVNSRFNS—–PTTQDLVYIDPSPDYCVRNESTGSL
MOUSEWNT5B ———-LELANSRFNQ—–PTPEDLVYVDPSPDYCLRNETTGSL
MOUSEWNT6 –MGTNDGKALLPAVRTLKP—–PGRADLLYAADSPDFCAPNRRTGSP
MOUSEWNT7A N-KRPTFLKIKKPLSYRK——-PMDTDLVYIELSPNYCEEDPVTGSV
MOUSEWNT7B L-RQPTFLRIKQLRSYQK——-PMETDLVYIEKSPNYCEEDAATGSV
MOUSEWNT8A –RAGNRAEGRWALTEAFLP—–STEAELIFLEGSPDYCNRNASLSIQ
MOUSEWNT8B –GAGNSAAGRGAIADTFRS—–ISTRELVHLEDSPDYCLENKTLGLL
MOUSEWNT9A TGEAGAISPPRGRASGSGGGD–PLPRTPELVHLDDSPSFCLAGRF–SP
MOUSEWNT9B LGRLELWAPAKPGGPAKG—–LAPRPGDLVYMEDSPSFCRPSKY–SP
MOUSEWNT10A GQLEPGPAGAPSPAPGTPGLR–RRASHSDLVYFEKSPDFCEREPRLDSA
MOUSEWNT10B GAFQP————-RLR–PRRLSGELVYFEKSPDFCERDPTLGSP
MOUSEWNT11 RKHLVPKDLDIRPVKDSE————LVYLQSSPDFCMKNEKVGSH
MOUSEWNT16 NMRRREKDQRQTPI————LKDDLLYVHKSPNYCVENKKLGIP
DrosophilaWg NSLRATYHFQLNPHNPEHKP—–PGSKDLVYLEPSPSFCEKNLRQGIL
DrosophilaWnt2 G-LRLVLSRKKHAGTARAQKPVLDWPKRMELIYLEASPNYCERSLQTGSQ
DrosophilaWnt3/5_short_ ———-LQIKDLQFKV—–PTAHDLIYLDESPDWCRNSYALHWP
hydraWnt A-NGERKIKDLIPKYKEYLP—–PSSLDFIYYEESPNYVK-NETLGIA
C_elegans_egl20 RLRRKERTERKIPL————RGNEMAYVHRSPSYCEKNLTAGIL

MOUSEWNT1 GTAGRACNSSSPALD—–GCELLC–CGRGHRTRTQRVTERCNCTFHW
MOUSEWNT2 GTAGRVCNLTSRGMD—–SCEVMC–CGRGYDTSHVTRMTKCECKFHW
MOUSEWNT2B GTAGRVCSKTSKGTD—–GCEIMC–CGRGYDTTRVTRVTQCECKFHW
MOUSEWNT3 GTRDRTCNVTSHGID—–GCDLLC–CGRGHNTRTEKRKEKCHCVFHW
MOUSEWNT3A GTRDRTCNVSSHGID—–GCDLLC–CGRGHNARTERRREKCHCVFHW
MOUSEWNT4 GTRGRTCNKTSKAID—–GCELLC–CGRGFHTAQVELAERCGCRFHW
MOUSEWNT5A GTQGRLCNKTSEGMD—–GCELMC–CGRGYDQFKTVQTERCHCKFHW
MOUSEWNT5B GTQGRLCNKTSEGMD—–GCELMC–CGRGYDRFKSVQVERCHCRFHW
MOUSEWNT6 GTRGRACNSSAPDLS—–GCDLLC–CGRGHRQESVQLEENCLCRFHW
MOUSEWNT7A GTQGRACNKTAPQAS—–GCDLMC–CGRGYNTHQYARVWQCNCKFHW
MOUSEWNT7B GTQGRLCNRTSPGAD—–GCDTMC–CGRGYNTHQYTKVWQCNCKFHW
MOUSEWNT8A GTEGRECLQNARSASRREQRSCGRLCTECGLQVEERRAEAVSSCDCNFQW
MOUSEWNT8B GTEGRECLRRGRALGRWERRSCRRLCGDCGLAVEERRAETVSSCNCKFHW
MOUSEWNT9A GTAGRRCHREKN———CESIC–CGRGHNTQSRVVTRPCQCQVRW
MOUSEWNT9B GTAGRVCSRDSS———CSSLC–CGRGYDTQSRMVVFSCHCQVQW
MOUSEWNT10A GTVGRLCNKSSTGPD—–GCGSMC–CGRGHNILRQTRSERCHCRFHW
MOUSEWNT10B GTRGRACNKTSRLLD—–GCGSLC–CGRGHNVLRQTRVERCHCRFHW
MOUSEWNT11 GTQDRQCNKTSNGSD—–SCDLMC–CGRGYNPYTDRVVERCHCKYHW
MOUSEWNT16 GTQGRECNRTSGGAD—–GCNLLC–CGRGYNTHVVRHVERCECKFIW
DrosophilaWg GTHGRQCNETSLGVD—–GCGLMC–CGRGYRRDEVVVVERCACTFHW
DrosophilaWnt2 GTSGRTCQRTGHGPQ—–SCDLLC–CGRGHNTQHIRRTTQCRCQFRW
DrosophilaWnt3/5_short_ GTHGRVCHKNSSGLE—–SCAILC–CGRGYNTKNIIVNERCNCKFHW
hydraWnt GTKGRSCNITSSGVD—–GCELMC–CQRGYNVNIVQKTHSCECKFVW
C_elegans_egl20 GTSGRECIHNSYSSE—–SCDLLC–CGRGYNTRLEIRQTQCECKFVW

MOUSEWNT1 CCHVSCRNCTHTRVLHECL—————–
MOUSEWNT2 CCAVRCQDCLEALDVHTCKAPKSADWATPT——
MOUSEWNT2B CCAVRCKECRNTVDVHTCKAPKKAEWLDQT——
MOUSEWNT3 CCYVSCQECIRIYDVHTCK—————–
MOUSEWNT3A CCYVSCQECTRVYDVHTCK—————–
MOUSEWNT4 CCFVKCRQCQRLVEMHTCR—————–
MOUSEWNT5A CCYVKCKKCTEIVDQFVCK—————–
MOUSEWNT5B CCFVRCKKCTEVVDQYVCK—————–
MOUSEWNT6 CCVVQCHRCRVRKELSLCL—————–
MOUSEWNT7A CCYVKCNTCSERTEMYTCK—————–
MOUSEWNT7B CCFVKCNTCSERTEVFTCK—————–
MOUSEWNT8A CCTVKCGQCRRVVSRYYCTRPVGSARPRGRGKDSAW
MOUSEWNT8B CCAVRCEQCRRRVTKYFCSRAERPPRGAAHKPGKNS
MOUSEWNT9A CCYVECRQCTQREEVYTCKG—————-
MOUSEWNT9B CCYVECQQCAQQELVYTCKR—————-
MOUSEWNT10A CCFVVCEECRITEWVSVCK—————–
MOUSEWNT10B CCYVLCDECKVTEWVNVCK—————–
MOUSEWNT11 CCYVTCRRCERTVERYVCK—————–
MOUSEWNT16 CCYVRCRRCESMTDVHTCK—————–
DrosophilaWg CCEVKCKLCRTKKVIYTCL—————–
DrosophilaWnt2 CCEVKCDECDESYEEFTCK—————–
DrosophilaWnt3/5_short_ CCQVKCEVCTKVLEEHTCK—————–
hydraWnt CCKVSCNSCIKMTPEYTCK—————–
C_elegans_egl20 CCEVKCKTCTEEVAVHTCK—————–