Publications

Recent papers from the Nusse Lab
(list all publications from PubMed)

Wu, Peng V., Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam,
          Hannah Walton, Maurizio Morri, Norma Neff, Robert B. West, and Roel
          Nusse. 2024. “A developmental biliary lineage program cooperates with
          constitutive Wnt activation to promote cell proliferation in embryonal
          hepatoblastoma.” BioRxiv: 2023.06.08.544267.

Azizoglu, D. Berfin, Karina Perez, Sherry Li Zheng, Shahadat Rahman, Ellen
          Youngsoo Rim, Teni Anbarchian, Matt Fish, Kyle M. Loh, Kristy Red-Horse,
         and Roel Nusse. 2024. “Liver size is predetermined in the neonate by
         adding lobules at the periphery.” BioRXive.

Sarkar, A., Y. Jin, B. C. DeFelice, C. Y. Logan, Y. Yang, T. Anbarchian, P. Wu,
          M. Morri, N. F. Neff, H. Nguyen, E. Rulifson, M. Fish, A. G. Kaye, A. M.
         Martinez Jaimes, and R. Nusse. 2023. “Intermittent fasting induces rapid
         hepatocyte proliferation to restore the hepatostat in the mouse liver.” Elife
         12. https://doi.org/10.7554/eLife.82311.

Rim, E. Y., and R. Nusse. 2023. “APEX2-Mediated Proximity Labeling of Wnt
         Receptor Interactors Upon Pathway Activation.” MicroPubl Biol 2023.

Rim, E. Y., H. Clevers, and R. Nusse. 2022. “The Wnt Pathway: From Signaling
         Mechanisms to Synthetic Modulators.” Annu Rev Biochem 91: 571-598.

Jin, Y., T. Anbarchian, P. Wu, A. Sarkar, M. Fish, W. C. Peng, and R. Nusse.
         2022. “Wnt signaling regulates hepatocyte cell division by a transcriptional
         repressor cascade.” Proc Natl Acad Sci U S A 119 (30): e2203849119.

Russell, J. P., X. Lim, A. Santambrogio, V. Yianni, Y. Kemkem, B. Wang, M.
          Fish, S. Haston, A. Grabek, S. Hallang, E. J. Lodge, A. L. Patist, A. Schedl,
         P. Mollard, R. Nusse, and C. L. Andoniadou. 2021. “Pituitary stem cells
          produce paracrine WNT signals to control the expansion of their
         descendant progenitor cells.” Elife 10. https://doi.org/10.7554/eLife.59142.

.Habara, O., C. Y. Logan, M. Kanai-Azuma, R. Nusse, and H. M. Takase. 2021.
          “WNT signaling in pre-granulosa cells is required for ovarian
         folliculogenesis and female fertility.” Development 148 (9).

Rim, E. Y., L. K. Kinney, and R. Nusse. 2020.”beta-catenin-mediated Wnt signal
         transduction proceeds through an endocytosis-independent mechanism.”
         Mol Biol Cell 31 (13): 1425-1436.

Miao, Y., A. Ha, W. de Lau, K. Yuki, A. J. M. Santos, C. You, M. H. Geurts, J.
          Puschhof, C. Pleguezuelos-Manzano, W. C. Peng, R. Senlice, C. Piani, J.
          W. Buikema, O. M. Gbenedio, M. Vallon, J. Yuan, S. de Haan, W. Hemrika,
          K. Rosch, L. T. Dang, D. Baker, M. Ott, P. Depeille, S. M. Wu, J. Drost, R.

          Nusse, J. P. Roose, J. Piehler, S. F. Boj, C. Y. Janda, H. Clevers, C. J.
          Kuo, and K. C. Garcia. 2020. “Next-Generation Surrogate Wnts Support
          Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.” Cell Stem
          Cell 27.

Zhao, L., Y. Jin, K. Donahue, M. Tsui, M. Fish, C. Y. Logan, B. Wang, and R.
         Nusse. 2019. “Tissue Repair in the Mouse Liver Following Acute Carbon
         Tetrachloride Depends on Injury-Induced Wnt/beta-Catenin Signaling.”
         Hepatology 69 (6): 2623-2635.

Xing, L., T. Anbarchian, J. M. Tsai, G. W. Plant, and R. Nusse. 2018. “Wnt/beta-
          catenin signaling regulates ependymal cell development and adult
         homeostasis.” Proc Natl Acad Sci U S A 115 (26): E5954-E5962.

Peng, W. C., C. Y. Logan, M. Fish, T. Anbarchian, F. Aguisanda, A. Alvarez-
          Varela, P. Wu, Y. Jin, J. Zhu, B. Li, M. Grompe, B. Wang, and R. Nusse.
         2018. “Inflammatory Cytokine TNFalpha Promotes the Long-Term
         Expansion of Primary Hepatocytes in 3D Culture.” Cell 175 (6): 1607-1619
         e15.

Nusse, Roel, and Hans Clevers. 2017. “Wnt/β-Catenin Signaling, Disease, and
         Emerging Therapeutic Modalities.” Cell 169 (6): 985-999.
         https://doi.org/10.1016/j.cell.2017.05.016.

Brown, K., K. M. Loh, and R. Nusse. 2017. “Live Imaging Reveals that the First
          Division of Differentiating Human Embryonic Stem Cells Often Yields
         Asymmetric Fates.” Cell Rep 21 (2): 301-307.
         doi:10.1016/j.celrep.2017.09.044.
         https://www.ncbi.nlm.nih.gov/pubmed/29020617.

Takase, H. M., and R. Nusse. 2016. “Paracrine Wnt/beta-catenin signaling
          mediates proliferation of undifferentiated spermatogonia in the adult mouse
         testis.” Proc Natl Acad Sci U S A 113 (11): E1489-97.

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