Recent papers from the Nusse Lab
(list all publications from PubMed)
Wu, Peng V., Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam,
Hannah Walton, Maurizio Morri, Norma Neff, Robert B. West, and Roel
Nusse. 2024. “A developmental biliary lineage program cooperates with
constitutive Wnt activation to promote cell proliferation in embryonal
hepatoblastoma.” BioRxiv: 2023.06.08.544267.
Azizoglu, D. Berfin, Karina Perez, Sherry Li Zheng, Shahadat Rahman, Ellen
Youngsoo Rim, Teni Anbarchian, Matt Fish, Kyle M. Loh, Kristy Red-Horse,
and Roel Nusse. 2024. “Liver size is predetermined in the neonate by
adding lobules at the periphery.” BioRXive.
Sarkar, A., Y. Jin, B. C. DeFelice, C. Y. Logan, Y. Yang, T. Anbarchian, P. Wu,
M. Morri, N. F. Neff, H. Nguyen, E. Rulifson, M. Fish, A. G. Kaye, A. M.
Martinez Jaimes, and R. Nusse. 2023. “Intermittent fasting induces rapid
hepatocyte proliferation to restore the hepatostat in the mouse liver.” Elife
12. https://doi.org/10.7554/eLife.82311.
Rim, E. Y., and R. Nusse. 2023. “APEX2-Mediated Proximity Labeling of Wnt
Receptor Interactors Upon Pathway Activation.” MicroPubl Biol 2023.
Rim, E. Y., H. Clevers, and R. Nusse. 2022. “The Wnt Pathway: From Signaling
Mechanisms to Synthetic Modulators.” Annu Rev Biochem 91: 571-598.
Jin, Y., T. Anbarchian, P. Wu, A. Sarkar, M. Fish, W. C. Peng, and R. Nusse.
2022. “Wnt signaling regulates hepatocyte cell division by a transcriptional
repressor cascade.” Proc Natl Acad Sci U S A 119 (30): e2203849119.
Russell, J. P., X. Lim, A. Santambrogio, V. Yianni, Y. Kemkem, B. Wang, M.
Fish, S. Haston, A. Grabek, S. Hallang, E. J. Lodge, A. L. Patist, A. Schedl,
P. Mollard, R. Nusse, and C. L. Andoniadou. 2021. “Pituitary stem cells
produce paracrine WNT signals to control the expansion of their
descendant progenitor cells.” Elife 10. https://doi.org/10.7554/eLife.59142.
.Habara, O., C. Y. Logan, M. Kanai-Azuma, R. Nusse, and H. M. Takase. 2021.
“WNT signaling in pre-granulosa cells is required for ovarian
folliculogenesis and female fertility.” Development 148 (9).
Rim, E. Y., L. K. Kinney, and R. Nusse. 2020.”beta-catenin-mediated Wnt signal
transduction proceeds through an endocytosis-independent mechanism.”
Mol Biol Cell 31 (13): 1425-1436.
Miao, Y., A. Ha, W. de Lau, K. Yuki, A. J. M. Santos, C. You, M. H. Geurts, J.
Puschhof, C. Pleguezuelos-Manzano, W. C. Peng, R. Senlice, C. Piani, J.
W. Buikema, O. M. Gbenedio, M. Vallon, J. Yuan, S. de Haan, W. Hemrika,
K. Rosch, L. T. Dang, D. Baker, M. Ott, P. Depeille, S. M. Wu, J. Drost, R.
Nusse, J. P. Roose, J. Piehler, S. F. Boj, C. Y. Janda, H. Clevers, C. J.
Kuo, and K. C. Garcia. 2020. “Next-Generation Surrogate Wnts Support
Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.” Cell Stem
Cell 27.
Zhao, L., Y. Jin, K. Donahue, M. Tsui, M. Fish, C. Y. Logan, B. Wang, and R.
Nusse. 2019. “Tissue Repair in the Mouse Liver Following Acute Carbon
Tetrachloride Depends on Injury-Induced Wnt/beta-Catenin Signaling.”
Hepatology 69 (6): 2623-2635.
Xing, L., T. Anbarchian, J. M. Tsai, G. W. Plant, and R. Nusse. 2018. “Wnt/beta-
catenin signaling regulates ependymal cell development and adult
homeostasis.” Proc Natl Acad Sci U S A 115 (26): E5954-E5962.
Peng, W. C., C. Y. Logan, M. Fish, T. Anbarchian, F. Aguisanda, A. Alvarez-
Varela, P. Wu, Y. Jin, J. Zhu, B. Li, M. Grompe, B. Wang, and R. Nusse.
2018. “Inflammatory Cytokine TNFalpha Promotes the Long-Term
Expansion of Primary Hepatocytes in 3D Culture.” Cell 175 (6): 1607-1619
e15.
Nusse, Roel, and Hans Clevers. 2017. “Wnt/β-Catenin Signaling, Disease, and
Emerging Therapeutic Modalities.” Cell 169 (6): 985-999.
https://doi.org/10.1016/j.cell.2017.05.016.
Brown, K., K. M. Loh, and R. Nusse. 2017. “Live Imaging Reveals that the First
Division of Differentiating Human Embryonic Stem Cells Often Yields
Asymmetric Fates.” Cell Rep 21 (2): 301-307.
doi:10.1016/j.celrep.2017.09.044.
https://www.ncbi.nlm.nih.gov/pubmed/29020617.
Takase, H. M., and R. Nusse. 2016. “Paracrine Wnt/beta-catenin signaling
mediates proliferation of undifferentiated spermatogonia in the adult mouse
testis.” Proc Natl Acad Sci U S A 113 (11): E1489-97.